Title : Ectopic expression of the TERE1 (UBIAD1) protein inhibits growth of renal clear cell carcinoma cells: altered metabolic phenotype associated with reactive oxygen species, nitric oxide and SXR target genes involved in cholesterol and lipid metabolism.

Pub. Date : 2013 Aug

PMID : 23759948






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 However, the profound effects of TERE1 relate to its prenyltransferase activity for synthesis of the bioactive quinones menaquinone and COQ10. Vitamin K 2 UbiA prenyltransferase domain containing 1 Homo sapiens
2 RT-PCR analysis determined that TERE1 activated several SXR targets known to regulate lipid metabolism, consistent with predictions based on its role in menaquinone synthesis. Vitamin K 2 UbiA prenyltransferase domain containing 1 Homo sapiens