Pub. Date : 2013 Sep
PMID : 23751277
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with atorvastatin (n = 10), but not with fluvastatin (n = 10), resulted in 3-fold higher expression of SLCO2B1 compared with placebo-treated patients (n = 9) (P < 0.05). | Atorvastatin | solute carrier organic anion transporter family member 2B1 | Homo sapiens |
| 2 | Here we show for the first time that atorvastatin treatment leads to increased expression of the membrane transporters SLCO2B1, ABCB1, and ABCG2 in human liver tissue, which potentially may counteract the efficacy of the treatment, and our findings may cast light on the mechanisms of clinical problems with adverse reactions and drug interactions in statin treatment. | Atorvastatin | solute carrier organic anion transporter family member 2B1 | Homo sapiens |