Title : Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID).

Pub. Date : 1990 Jul 26

PMID : 2374612






1 Functional Relationships(s)
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1 This reveals an evolutionarily conserved core which corresponds precisely to the 180-residue DNA binding/activation domain determined for yeast TFIID, a near absolute conservation of component structural motifs (direct repeats, central basic core/lysine repeat, and sigma homology), providing further support for their functional importance, and a unique N-terminal structure that suggests involvement in species-specific regulatory factor interactions. Lysine TATA-box binding protein Homo sapiens