Title : MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion.

Pub. Date : 2013 Aug

PMID : 23744646






2 Functional Relationships(s)
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1 Here, we investigated the signaling properties of the C-type lectin MGL and show that MGL engagement by agonistic antibodies or carbohydrate ligands couples to TLR signal transduction for increased IL-10 and TNF-alpha secretion by human monocyte-derived DCs. Carbohydrates C-type lectin domain containing 10A Homo sapiens
2 Here, we investigated the signaling properties of the C-type lectin MGL and show that MGL engagement by agonistic antibodies or carbohydrate ligands couples to TLR signal transduction for increased IL-10 and TNF-alpha secretion by human monocyte-derived DCs. Carbohydrates C-type lectin domain containing 10A Homo sapiens