Title : Activation of KCa3.1 by SKA-31 induces arteriolar dilatation and lowers blood pressure in normo- and hypertensive connexin40-deficient mice.

Pub. Date : 2013 Sep

PMID : 23734697






1 Functional Relationships(s)
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1 KEY RESULTS: In wild-type mice, the KCa3.1-activator SKA-31 induced pronounced concentration-dependent arteriolar EDH-type dilatations, amounting to ~40% of maximal dilatation, and enhanced the effects of ACh. Acetylcholine potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 Mus musculus