Title : The suppression effects of thalidomide on human lung fibroblasts: cell proliferation, vascular endothelial growth factor release, and collagen production.

Pub. Date : 2013 Aug

PMID : 23722461






1 Functional Relationships(s)
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1 RESULTS: Thalidomide (20 muM) not only inhibited cell proliferation after 24 h [fold increase of cell number, 0.85 +- 0.09 vs. 1.47 +- 0.14 (treatment vs. control group); P < 0.01] and 48 h of incubation (0.85 +- 0.10 vs. 1.97 +- 0.12; P < 0.001), it also inhibited cell migration and slowed wound closure at 24 h (P < 0.001). Thalidomide latexin Homo sapiens