Title : Effects of di(n-butyl) and monobutyl phthalate on steroidogenesis pathways in the murine Leydig tumor cell line MLTC-1.

Pub. Date : 2013 Sep

PMID : 23712133






2 Functional Relationships(s)
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Protein Name
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1 The mRNA levels of the side-chain cleavage enzyme (P450scc), cytochrome p450c17 (P450c17) and 3beta-hydroxy-steroid dehydrogenase (3betaHSD) were significantly reduced in the phthalate-exposed groups, whereas, the transcription and translation of insulin-like hormone 3 (INSL3) was affected by DBP and MBP. phthalic acid cytochrome P450, family 17, subfamily a, polypeptide 1 Mus musculus
2 The mRNA levels of the side-chain cleavage enzyme (P450scc), cytochrome p450c17 (P450c17) and 3beta-hydroxy-steroid dehydrogenase (3betaHSD) were significantly reduced in the phthalate-exposed groups, whereas, the transcription and translation of insulin-like hormone 3 (INSL3) was affected by DBP and MBP. phthalic acid cytochrome P450, family 17, subfamily a, polypeptide 1 Mus musculus