Title : Ursolic acid improves domoic acid-induced cognitive deficits in mice.

Pub. Date : 2013 Sep 1

PMID : 23707761






2 Functional Relationships(s)
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1 Evidence shows that UA can activate PI3K/Akt signaling and suppress Forkhead box protein O1 (FoxO1) activity. ursolic acid thymoma viral proto-oncogene 1 Mus musculus
2 Moreover, UA attenuated the mitochondrial dysfunction and cognitive deficits through promoting Akt phosphorylation and FoxO1 nuclear exclusion in the hippocampus of DA-treated mice. ursolic acid thymoma viral proto-oncogene 1 Mus musculus