Pub. Date : 2013
PMID : 23696794
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MiR-339-5p regulates the growth, colony formation and metastasis of colorectal cancer cells by targeting PRL-1. | mir-339-5p | protein tyrosine phosphatase 4A1 | Homo sapiens |
| 2 | Here, we report that miR-339-5p is a tumor suppressor by regulating expression of PRL-1. | mir-339-5p | protein tyrosine phosphatase 4A1 | Homo sapiens |
| 3 | Overexpression of miR-339-5p would also reduce the expression of PRL-1 mRNA and protein. | mir-339-5p | protein tyrosine phosphatase 4A1 | Homo sapiens |
| 4 | In conclusion, our results demonstrate that miR-339-5p functions as a tumor suppressor and plays a role in inhibiting growth and metastasis of CRC cells through targeting PRL-1 and regulating p-ERK1/2 .These findings suggest that miR-339-5p may be useful as a new potential therapeutic target for CRC. | mir-339-5p | protein tyrosine phosphatase 4A1 | Homo sapiens |
| 5 | In conclusion, our results demonstrate that miR-339-5p functions as a tumor suppressor and plays a role in inhibiting growth and metastasis of CRC cells through targeting PRL-1 and regulating p-ERK1/2 .These findings suggest that miR-339-5p may be useful as a new potential therapeutic target for CRC. | mir-339-5p | protein tyrosine phosphatase 4A1 | Homo sapiens |