Pub. Date : 2013 May
PMID : 23688998
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effect of dexamethasone on expression of interleukin-21 and phospho-STAT3 in a murine model of chronic asthma]. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 2 | OBJECTIVE: To investigate the effects of dexamethasone on the expression of interleukin-21 (IL-21) and phospho- STAT3 (p-STAT3) in a murine model of chronic asthma. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 3 | OBJECTIVE: To investigate the effects of dexamethasone on the expression of interleukin-21 (IL-21) and phospho- STAT3 (p-STAT3) in a murine model of chronic asthma. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 4 | Compared with the control group, the asthmatic group showed significantly increased protein expressions of IL-21 and p-STAT3 (P<0.05), which were reduced by dexamethasone intervention (P/0.05). | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 5 | CONCLUSION: Dexamethasone can inhibit the expression of IL-21 and p-STAT3 in the murine model of chronic asthma, suggesting the importance of IL-21/STAT3 signaling pathway in the therapeutic mechanisms of dexamethasone for asthma. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 6 | CONCLUSION: Dexamethasone can inhibit the expression of IL-21 and p-STAT3 in the murine model of chronic asthma, suggesting the importance of IL-21/STAT3 signaling pathway in the therapeutic mechanisms of dexamethasone for asthma. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 7 | CONCLUSION: Dexamethasone can inhibit the expression of IL-21 and p-STAT3 in the murine model of chronic asthma, suggesting the importance of IL-21/STAT3 signaling pathway in the therapeutic mechanisms of dexamethasone for asthma. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |
| 8 | CONCLUSION: Dexamethasone can inhibit the expression of IL-21 and p-STAT3 in the murine model of chronic asthma, suggesting the importance of IL-21/STAT3 signaling pathway in the therapeutic mechanisms of dexamethasone for asthma. | Dexamethasone | signal transducer and activator of transcription 3 | Mus musculus |