Title : A pH-regulated quality control cycle for surveillance of secretory protein assembly.

Pub. Date : 2013 Jun 27

PMID : 23685074






1 Functional Relationships(s)
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1 At the lower pH of the cisGolgi, conformational rearrangements of this peptide, likely involving protonation of ERp44"s active cysteine, simultaneously unmask the substrate binding site and -RDEL motif, allowing capture of orphan secretory protein subunits and ER retrieval via KDEL receptors. Cysteine endoplasmic reticulum protein 44 Homo sapiens