Title : Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion.

Pub. Date : 2013 Aug

PMID : 23683514






2 Functional Relationships(s)
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1 OBJECTIVE: We sought to investigate the production of the TH17-associated cytokines IL-17A and IL-22 in culture in patients with moderate-to-severe asthma defined on the basis of their clinical response to steroids and the susceptibility of this response to inhibition by steroids and the active form of vitamin D, 1alpha,25-dihydroxyvitamin D3 (1,25[OH]2D3). Steroids interleukin 17A Homo sapiens
2 OBJECTIVE: We sought to investigate the production of the TH17-associated cytokines IL-17A and IL-22 in culture in patients with moderate-to-severe asthma defined on the basis of their clinical response to steroids and the susceptibility of this response to inhibition by steroids and the active form of vitamin D, 1alpha,25-dihydroxyvitamin D3 (1,25[OH]2D3). Steroids interleukin 17A Homo sapiens