Pub. Date : 2013 Sep
PMID : 23681145
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | miR-21 contributes to xenon-conferred amelioration of renal ischemia-reperfusion injury in mice. | Xenon | microRNA 21a | Mus musculus |
| 2 | The role of microRNA, miR-21, in renal protection conferred by the delayed xenon preconditioning was examined using in vivo knockdown of miR-21 and analysis of miR-21 target pathways. | Xenon | microRNA 21a | Mus musculus |
| 3 | Xenon preconditioning significantly increased the expression of miR-21 in the mouse kidney. | Xenon | microRNA 21a | Mus musculus |
| 4 | A locked nucleic acid-modified anti-miR-21, given before xenon preconditioning, knocked down miR-21 effectively, and exacerbated subsequent renal ischemia-reperfusion injury. | Xenon | microRNA 21a | Mus musculus |
| 5 | CONCLUSIONS: These results indicate that miR-21 contributes to the renoprotective effect of xenon preconditioning. | Xenon | microRNA 21a | Mus musculus |