Title : A unique spumavirus Gag N-terminal domain with functional properties of orthoretroviral matrix and capsid.

Pub. Date : 2013 May

PMID : 23675305






3 Functional Relationships(s)
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1 In addition, PFV Gag interacts with the FV Envelope (Env) protein to facilitate budding of infectious particles. Glycosaminoglycans endogenous retrovirus group K member 20 Homo sapiens
2 We present the crystal structure of a dimeric amino terminal domain from PFV, Gag-NtD, both free and in complex with the leader peptide of PFV Env. Glycosaminoglycans endogenous retrovirus group K member 20 Homo sapiens
3 Furthermore, we present structural, biochemical and virological data that reveal the molecular details of the essential Gag-Env interaction and in addition we also examine the specificity of Trim5alpha restriction of PFV. Glycosaminoglycans endogenous retrovirus group K member 20 Homo sapiens