Title : [Effect of berberine, liensinine and neferine on HERG channel expression].

Pub. Date : 2013 Jan

PMID : 23672049






5 Functional Relationships(s)
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1 [Effect of berberine, liensinine and neferine on HERG channel expression]. neferine potassium voltage-gated channel subfamily H member 2 Homo sapiens
2 OBJECTIVE: Immunofluorescence and Western blot methods were adopted for qualitative and quantitative detections of the effect of different concentrations of berberine, liensinine and neferine on the expression of stable transfection in HERG potassium channel in HEK-293 cells, as well as the effect of different concentrations of berberine on protein expression of Ikr channel in cardiac muscular tissues, in order to investigate the anti-arrhythmic mechanism of berberine, liensinine and neferine. neferine potassium voltage-gated channel subfamily H member 2 Homo sapiens
3 OBJECTIVE: Immunofluorescence and Western blot methods were adopted for qualitative and quantitative detections of the effect of different concentrations of berberine, liensinine and neferine on the expression of stable transfection in HERG potassium channel in HEK-293 cells, as well as the effect of different concentrations of berberine on protein expression of Ikr channel in cardiac muscular tissues, in order to investigate the anti-arrhythmic mechanism of berberine, liensinine and neferine. neferine potassium voltage-gated channel subfamily H member 2 Homo sapiens
4 Immunofluorescence method as well as confocal laser microscope were used to detect the effect of different concentrations of berberine, liensinine and neferine on protein expression of HERG channel. neferine potassium voltage-gated channel subfamily H member 2 Homo sapiens
5 Western blot method was used to detect the effect of different concentrations of berberine on protein expression of Ikr channel in cardiac muscular tissues as well as the effect of berberine, liensinine and neferine on protein expression of stable transfection in HERG potassium channel in HEK-293 cells. neferine potassium voltage-gated channel subfamily H member 2 Homo sapiens