Title : COX-2 regulates E-cadherin expression through the NF-κB/Snail signaling pathway in gastric cancer.

Pub. Date : 2013 Jul

PMID : 23670240






1 Functional Relationships(s)
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1 Treatment of the SGC7901 cells (which express high levels of COX-2) with celecoxib, a COX-2 inhibitor, not only led to a marked dose- and time-dependent decrease in the expression of COX-2, NF-kappaB and Snail, but also led to a significant increase in the expression of E-cadherin, and this was associated with a reduction in cell invasion. Celecoxib snail family transcriptional repressor 1 Homo sapiens