Title : Idebenone prevents human optic nerve head astrocytes from oxidative stress, apoptosis, and senescence by stabilizing BAX/Bcl-2 ratio.

Pub. Date : 2013 Jun-Jul

PMID : 23661043






2 Functional Relationships(s)
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1 Idebenone prevents human optic nerve head astrocytes from oxidative stress, apoptosis, and senescence by stabilizing BAX/Bcl-2 ratio. idebenone BCL2 associated X, apoptosis regulator Homo sapiens
2 When ONHA cells were treated with idebenone and H2O2, real-time polymerase chain reaction and Western blot analysis yielded an increased expression of Bcl-2 and a decrease of BAX compared with those cells that were treated with H2O2 only. idebenone BCL2 associated X, apoptosis regulator Homo sapiens