Pub. Date : 2013 Jul 15
PMID : 23657854
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reactive oxygen species and IRF1 stimulate IFNalpha production by proximal tubules during ischemic AKI. | Reactive Oxygen Species | interferon alpha | Mus musculus |
| 2 | Furthermore, we found that ROS induced IFNalpha expression by renal tubules in vitro. | Reactive Oxygen Species | interferon alpha | Mus musculus |
| 3 | Altogether our data support the following autocrine pathway in renal tubular cells: ROS > IRF1 > IFNalpha > IFNARI > CXCL2. | Reactive Oxygen Species | interferon alpha | Mus musculus |