Title : Nonempirical energetic analysis of reactivity and covalent inhibition of fatty acid amide hydrolase.

Pub. Date : 2013 Jun 6

PMID : 23654226






1 Functional Relationships(s)
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1 A comparison of FAAH acylation with a reference reaction in water suggests that transition-state stabilization is crucial for catalysis because the activation energy barrier falls by 6 kcal/mol in the presence of the active site. Water fatty acid amide hydrolase Homo sapiens