Title : Native Cu(A) redox sites are largely resilient to pH variations within a physiological range.

Pub. Date : 2013 Jun 14

PMID : 23652317






1 Functional Relationships(s)
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1 Previous studies on engineered CuA centres have shown that one of the histidine ligands is protonated and dissociated from the metal site at physiological pH values, thus suggesting a role in regulating proton-coupled electron transfer of cytochrome c oxidases in vivo. Histidine cytochrome c, somatic Homo sapiens