Title : Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates.

Pub. Date : 2013 Sep

PMID : 23649127






1 Functional Relationships(s)
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1 However, C:G>T:A changes within CpG dinucleotides were often resistant to the UDG treatment as a consequence of 5-methyl cytosine being deaminated to thymine rather than uracil. 5-Methylcytosine uracil DNA glycosylase Homo sapiens