Title : PPARĪ“ inhibits UVB-induced secretion of MMP-1 through MKP-7-mediated suppression of JNK signaling.

Pub. Date : 2013 Nov

PMID : 23639976






1 Functional Relationships(s)
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1 Finally, in HR-1 hairless mice exposed to UVB, administration of GW501516 significantly reduced wrinkle formation and skin thickness, downregulated MMP-1 and JNK phosphorylation, and restored the levels of MKP-7, types I and III collagen. GW 501516 dual specificity phosphatase 16 Mus musculus