Pub. Date : 2013 Jul
PMID : 23637402
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that Gag assembly induced the aggregation of small Env clusters into larger domains and that these domains were completely immobile. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 2 | Truncation of the cytoplasmic tail (CT) of Env abrogated Gag"s ability to induce Env clustering and restored Env mobility at assembly sites, both of which correlated with increased Env-induced fusion of infected and uninfected cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 3 | Truncation of the cytoplasmic tail (CT) of Env abrogated Gag"s ability to induce Env clustering and restored Env mobility at assembly sites, both of which correlated with increased Env-induced fusion of infected and uninfected cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 4 | Truncation of the cytoplasmic tail (CT) of Env abrogated Gag"s ability to induce Env clustering and restored Env mobility at assembly sites, both of which correlated with increased Env-induced fusion of infected and uninfected cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 5 | Truncation of the cytoplasmic tail (CT) of Env abrogated Gag"s ability to induce Env clustering and restored Env mobility at assembly sites, both of which correlated with increased Env-induced fusion of infected and uninfected cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 6 | Hence, while Env trapping by Gag secures Env incorporation into viral particles, Env clustering and its sequestration at assembly sites likely also leads to the repression of its fusion function, and thus, by preventing the formation of syncytia, Gag helps to secure efficient transfer of viral particles to target cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 7 | Hence, while Env trapping by Gag secures Env incorporation into viral particles, Env clustering and its sequestration at assembly sites likely also leads to the repression of its fusion function, and thus, by preventing the formation of syncytia, Gag helps to secure efficient transfer of viral particles to target cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |
| 8 | Hence, while Env trapping by Gag secures Env incorporation into viral particles, Env clustering and its sequestration at assembly sites likely also leads to the repression of its fusion function, and thus, by preventing the formation of syncytia, Gag helps to secure efficient transfer of viral particles to target cells. | Glycosaminoglycans | endogenous retrovirus group K member 20 | Homo sapiens |