Title : Multilevel pharmacological manipulation of adenosine-prostaglandin E₂/cAMP nexus in the tumor microenvironment: a 'two hit' therapeutic opportunity.

Pub. Date : 2013 Jul

PMID : 23619528






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Ectonucleotidases (CD39 and CD73)-generated extracellular adenosine and cyclooxygenase-2 (COX2)-derived prostaglandin E2 (PGE2) are amongst the tumor microenvironmental factors that have emerged as attractive targets in this regard. Dinoprostone 5'-nucleotidase ecto Homo sapiens
2 Ectonucleotidases (CD39 and CD73)-generated extracellular adenosine and cyclooxygenase-2 (COX2)-derived prostaglandin E2 (PGE2) are amongst the tumor microenvironmental factors that have emerged as attractive targets in this regard. Dinoprostone 5'-nucleotidase ecto Homo sapiens