Title : Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro.

Pub. Date : 2013

PMID : 23616769






3 Functional Relationships(s)
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Protein Name
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1 EGCG inhibited interleukin (IL)-1beta, transforming growth factor beta, IL-8, and chemokine (C-C motif) ligand 2 (CCL2) release by stimulated FLS and/or THP-1 cells in a dose-dependent manner. epigallocatechin gallate C-C motif chemokine ligand 2 Homo sapiens
2 EGCG inhibited interleukin (IL)-1beta, transforming growth factor beta, IL-8, and chemokine (C-C motif) ligand 2 (CCL2) release by stimulated FLS and/or THP-1 cells in a dose-dependent manner. epigallocatechin gallate C-C motif chemokine ligand 2 Homo sapiens
3 Furthermore, MbetaCD enhanced the inflammatory response to CPP crystals increasing IL-8 and CCL2 secretion which was inhibited by EGCG in a dose-dependent manner. epigallocatechin gallate C-C motif chemokine ligand 2 Homo sapiens