Title : Structure-dependent activities of hydroxylated polybrominated diphenyl ethers on human estrogen receptor.

Pub. Date : 2013 Jul 5

PMID : 23603053






4 Functional Relationships(s)
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Protein Name
Organism
1 The good correlation between estrogenic activity and ER binding affinity of the low-brominated OH-PBDEs strongly suggest that these compounds induce ER transcriptional activity by binding directly with ER. oh-pbdes estrogen receptor 1 Homo sapiens
2 The good correlation between estrogenic activity and ER binding affinity of the low-brominated OH-PBDEs strongly suggest that these compounds induce ER transcriptional activity by binding directly with ER. oh-pbdes estrogen receptor 1 Homo sapiens
3 The good correlation between estrogenic activity and ER binding affinity of the low-brominated OH-PBDEs strongly suggest that these compounds induce ER transcriptional activity by binding directly with ER. oh-pbdes estrogen receptor 1 Homo sapiens
4 Molecular docking analysis of the ER/OH-PBDE complexes revealed two distinctive binding modes between low- and high-brominated OH-PBDEs which provided rationale for the difference in their ER activity. oh-pbdes estrogen receptor 1 Homo sapiens