Title : Tumor hypoxia and metabolism -- towards novel anticancer approaches.

Pub. Date : 2013 May

PMID : 23597945






1 Functional Relationships(s)
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1 In addition, we demonstrated that the Myc/HIF-1-targeted glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzing a key step producing the NADH cofactor, activates the Akt pathway, thereby upregulating expression of the anti-apoptotic Bcl-xL. NAD BCL2 like 1 Homo sapiens