Title : cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis.

Pub. Date : 2013 May 31

PMID : 23595987






1 Functional Relationships(s)
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1 Additionally, CRTC2 inhibition resulted in reduced expression of several glucagon-induced pyridoxal 5"-phosphate-dependent enzymes that convert amino acids to gluconeogenic intermediates, suggesting that it may control substrate availability as well as gluconeogenic gene expression. Pyridoxal Phosphate CREB regulated transcription coactivator 2 Homo sapiens