Title : Thiophene-core estrogen receptor ligands having superagonist activity.

Pub. Date : 2013 Apr 25

PMID : 23586645






3 Functional Relationships(s)
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1 Thiophene-core estrogen receptor ligands having superagonist activity. Thiophenes estrogen receptor 1 Homo sapiens
2 To probe the importance of the heterocyclic core of estrogen receptor (ER) ligands, we prepared a series of thiophene-core ligands by Suzuki cross-coupling of aryl boronic acids with bromo-thiophenes and we assessed their receptor binding and cell biological activities. Thiophenes estrogen receptor 1 Homo sapiens
3 To probe the importance of the heterocyclic core of estrogen receptor (ER) ligands, we prepared a series of thiophene-core ligands by Suzuki cross-coupling of aryl boronic acids with bromo-thiophenes and we assessed their receptor binding and cell biological activities. Thiophenes estrogen receptor 1 Homo sapiens