Title : MicroRNA 125 represses nonsense-mediated mRNA decay by regulating SMG1 expression.

Pub. Date : 2013 May 24

PMID : 23583196






1 Functional Relationships(s)
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1 In human cells, overexpression of miR-125 represses the endogenous levels of SMG1 protein and suppresses the NMD pathway; however, knockdown of miR-125 up-regulates the NMD pathway. mir-125 SMG1 nonsense mediated mRNA decay associated PI3K related kinase Homo sapiens