Title : Matrix metalloproteinases and blood-brain barrier disruption in acute ischemic stroke.

Pub. Date : 2013

PMID : 23565108






1 Functional Relationships(s)
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1 Reactive oxygen species can enhance the effects of tPA on MMP activation through the loss of caveolin-1 (cav-1), a protein encoded in the cav-1 gene that serves as a critical determinant of BBB permeability. Reactive Oxygen Species chromosome 20 open reading frame 181 Homo sapiens