Pub. Date : 2013 Jun 1
PMID : 23564507
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quercetin activated JNK and increased the expression levels of c-Jun and p53-dependent Bax. | Quercetin | tumor protein p53 | Homo sapiens |
| 2 | Blockade of JNK activation by overexpression of dominant negative JNK1 suppressed apoptosis by quercetin via inhibition of caspase-3 activation and reduction of p53 and Bax expression. | Quercetin | tumor protein p53 | Homo sapiens |
| 3 | Taken together, the JNK-p53 pathway is involved in quercetin-induced apoptosis, and simultaneous inactivation of GSK-3beta can attenuate apoptosis in normal bronchial epithelial cells. | Quercetin | tumor protein p53 | Homo sapiens |