Title : Simultaneous inactivation of GSK-3β suppresses quercetin-induced apoptosis by inhibiting the JNK pathway.

Pub. Date : 2013 Jun 1

PMID : 23564507






2 Functional Relationships(s)
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1 Quercetin activated JNK and increased the expression levels of c-Jun and p53-dependent Bax. Quercetin BCL2 associated X, apoptosis regulator Homo sapiens
2 Blockade of JNK activation by overexpression of dominant negative JNK1 suppressed apoptosis by quercetin via inhibition of caspase-3 activation and reduction of p53 and Bax expression. Quercetin BCL2 associated X, apoptosis regulator Homo sapiens