Title : Caffeine-induced endothelial cell death and the inhibition of angiogenesis.

Pub. Date : 2013 Mar

PMID : 23560237






2 Functional Relationships(s)
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1 In addition, caffeine up-regulated caspase-3 and down-regulated Bcl-2 at the protein level. Caffeine caspase 3 Homo sapiens
2 These results suggest that the inhibitory effect of caffeine on angiogenesis is associated, at least in part, with its induction of endothelial cell apoptosis, probably mediated by a caspase-3 dependent mechanism. Caffeine caspase 3 Homo sapiens