Title : A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression.

Pub. Date : 2013 Nov

PMID : 23558526






1 Functional Relationships(s)
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1 JAK2(V617F)-dependent ROS elevation was partly mediated by an AKT-induced decrease in catalase expression and was accompanied by an increased number of 8-oxo-guanines and DNA double-strand breaks (DSBs). dsbs thymoma viral proto-oncogene 1 Mus musculus