Title : Mammalian target of rapamycin inhibitors induce tumor cell apoptosis in vivo primarily by inhibiting VEGF expression and angiogenesis.

Pub. Date : 2013

PMID : 23533410






1 Functional Relationships(s)
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1 Mice challenged with p27-VEGF transfected tumor cells were more resistant to the antiangiogenic and apoptotic effects of the rapalog, temsirolimus, and active site mTOR inhibitor, pp242. PP242 vascular endothelial growth factor A Mus musculus