Title : Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides.

Pub. Date : 2013 Apr

PMID : 23530136






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Heteromeric cone CNGA3 (A3) + CNGB3 (B3) channels are inhibited by membrane phosphoinositides (PIP(n)), including phosphatidylinositol 3,4,5-triphosphate (PIP(3)) and phosphatidylinositol 4,5-bisphosphate (PIP(2)), demonstrating a decrease in apparent affinity for cyclic guanosine monophosphate (cGMP). phosphatidylinositol 3,4,5-triphosphate cyclic nucleotide gated channel subunit alpha 3 Homo sapiens