Pub. Date : 2013 Jun 7
PMID : 23519695
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Overexpression of miR-144 reduces ABCA1 expression and attenuates cholesterol efflux to apolipoproteinA1 in macrophages. | Cholesterol | microRNA 144 | Mus musculus |
| 2 | Thus, miR-144 seems to regulate both macrophage cholesterol efflux and HDL biogenesis in the liver. | Cholesterol | microRNA 144 | Mus musculus |
| 3 | CONCLUSIONS: miR-144 regulates cholesterol metabolism via suppressing ABCA1 expression and modulation of miRNAs may represent a potential therapeutical intervention for treating dyslipidemia and atherosclerotic vascular disease. | Cholesterol | microRNA 144 | Mus musculus |