Title : Preferential eradication of acute myelogenous leukemia stem cells by fenretinide.

Pub. Date : 2013 Apr 2

PMID : 23513221






3 Functional Relationships(s)
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1 Fenretinide exerted a selective cytotoxic effect on primary AML CD34(+) cells, especially the LSC-enriched CD34(+)CD38(-) subpopulation, whereas no significant effect was observed on normal counterparts. Fenretinide CD34 molecule Homo sapiens
2 Fenretinide exerted a selective cytotoxic effect on primary AML CD34(+) cells, especially the LSC-enriched CD34(+)CD38(-) subpopulation, whereas no significant effect was observed on normal counterparts. Fenretinide CD34 molecule Homo sapiens
3 Methylcellulose colony formation assays further showed that fenretinide significantly suppressed the formation of colonies derived from AML CD34(+) cells but not those from normal CD34(+) cells. Fenretinide CD34 molecule Homo sapiens