Title : Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle.

Pub. Date : 2013 May 3

PMID : 23504317






1 Functional Relationships(s)
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1 In addition, reductive carboxylation of alpha-ketoglutarate by isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) was recently shown to be a major source of citrate synthesis from glutamine. Citric Acid isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens