Title : Implication of JNK pathway on tau pathology and cognitive decline in a senescence-accelerated mouse model.

Pub. Date : 2013 Jun

PMID : 23501261






1 Functional Relationships(s)
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1 Among them, cognitive impairments and abnormal hyperphosphorylation of tau are ameliorated by the phosphodiesterase 5 inhibitor sildenafil, possibly through the modulation of Cdk5/p25 and Akt/GSK-3beta pathways. Sildenafil Citrate thymoma viral proto-oncogene 1 Mus musculus