Title : Heme levels are increased in human failing hearts.

Pub. Date : 2013 May 7

PMID : 23500306






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The rate-limiting enzyme in heme synthesis, delta-aminolevulinic acid synthase 2 (ALAS2), was significantly upregulated in HF. Heme 5'-aminolevulinate synthase 2 Homo sapiens
2 The rate-limiting enzyme in heme synthesis, delta-aminolevulinic acid synthase 2 (ALAS2), was significantly upregulated in HF. Heme 5'-aminolevulinate synthase 2 Homo sapiens
3 Overexpression of ALAS2 in H9c2 cardiac myoblasts resulted in increased heme levels, and hypoxia and erythropoietin treatment increased heme production through upregulation of ALAS2. Heme 5'-aminolevulinate synthase 2 Homo sapiens
4 Overexpression of ALAS2 in H9c2 cardiac myoblasts resulted in increased heme levels, and hypoxia and erythropoietin treatment increased heme production through upregulation of ALAS2. Heme 5'-aminolevulinate synthase 2 Homo sapiens