Title : Profibrotic activities for matrix metalloproteinase-8 during bleomycin-mediated lung injury.

Pub. Date : 2013 Apr 15

PMID : 23487425






1 Functional Relationships(s)
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1 Whereas bleomycin-treated Mmp-8(-/-) and WT mice have similar lung levels of several pro- and antifibrotic mediators (TGF-beta, IL-13, JE, and IFN-gamma), Mmp-8(-/-) mice have higher lung levels of IFN-gamma-inducible protein-10 (IP-10) and MIP-1alpha. Bleomycin interferon gamma Mus musculus