Title : A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic.

Pub. Date : 2013 Jun

PMID : 23486518






1 Functional Relationships(s)
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1 The half-maximal inhibitory concentration of PU-14 on rat UT-B-mediated urea transport was ~0.8 mumol/l, and it did not affect urea transport in mouse erythrocytes lacking UT-B but inhibited UT-A-type urea transporters, with 36% inhibition at 4 mumol/l. Urea solute carrier family 14 member 1 (Kidd blood group) Rattus norvegicus