Title : Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma.

Pub. Date : 2014 Feb 20

PMID : 23474763






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 High-risk HPV E6 inactivates p53 through two distinct mechanisms; association with E6AP to degrade p53 and association with p300 to block p300-mediated p53 acetylation and activation. e6ap tumor protein p53 Homo sapiens
2 High-risk HPV E6 inactivates p53 through two distinct mechanisms; association with E6AP to degrade p53 and association with p300 to block p300-mediated p53 acetylation and activation. e6ap tumor protein p53 Homo sapiens
3 High-risk HPV E6 inactivates p53 through two distinct mechanisms; association with E6AP to degrade p53 and association with p300 to block p300-mediated p53 acetylation and activation. e6ap tumor protein p53 Homo sapiens