Title : Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity.

Pub. Date : 2013 May

PMID : 23474502






2 Functional Relationships(s)
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1 alpha-Naphthoflavone was determined to be a potent MROD inhibitor of both CYP1A4 and CYP1A5. alpha-naphthoflavone cytochrome P450 1A2 Gallus gallus
2 Stronger inhibition of MROD activity was found in CYP1A5 than CYP1A4 by relatively small molecules alpha-naphthoflavone, piperonyl butoxide and furafylline. alpha-naphthoflavone cytochrome P450 1A2 Gallus gallus