Title : The ruthenium NO donor, [Ru(bpy)2(NO)SO3](PF6), inhibits inflammatory pain: involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway.

Pub. Date : 2013 Apr

PMID : 23470198






1 Functional Relationships(s)
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1 The inhibitory effect of complex I in the carrageenin-induced hyperalgesia, MPO activity and formalin was prevented by the treatment with ODQ, KT5823 and glybenclamide, indicating that complex I inhibits inflammatory hyperalgesia by activating the cGMP/PKG/ATP-sensitive potassium channel signaling pathway. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one protein kinase cGMP-dependent 1 Homo sapiens