Pub. Date : 2013 Jun
PMID : 23459077
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNAX-activating protein of 12kDa (DAP12) is a member of type I transmembrane adapter proteins containing immunoreceptor tyrosine-based activation motifs (ITAMs). | Tyrosine | transmembrane immune signaling adaptor TYROBP | Homo sapiens |
| 2 | DNAX-activating protein of 12kDa (DAP12) is a member of type I transmembrane adapter proteins containing immunoreceptor tyrosine-based activation motifs (ITAMs). | Tyrosine | transmembrane immune signaling adaptor TYROBP | Homo sapiens |
| 3 | TREM-2 ligation leads to the activation of Src family kinases, phosphorylation of tyrosine residues in the ITAM of DAP12, recruitment of the Syk and ZAP70 tyrosine kinases and initiation of an intracellular signaling cascade. | Tyrosine | transmembrane immune signaling adaptor TYROBP | Homo sapiens |