Title : Clinical perspectives on human genetic screening to prevent nevirapine toxicity.

Pub. Date : 2012 Sep 1

PMID : 23439719






1 Functional Relationships(s)
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1 Associations were identified with HLA-Cw*04, HLA-B*35, HLA-DRB*01 and CYP2B6 516G>T (rs3745274); however, positive predictive values for these genetic markers were low, and most nevirapine-associated adverse events occurred in patients without these markers. Nevirapine cytochrome P450 family 2 subfamily B member 6 Homo sapiens