Title : [Experimental study on delta-tocotrienol inhibits the Wnt pathway in the colon cancer cell SW620].

Pub. Date : 2012 Nov

PMID : 23424864






8 Functional Relationships(s)
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1 [Experimental study on delta-tocotrienol inhibits the Wnt pathway in the colon cancer cell SW620]. tocotrienol, delta Wnt family member 1 Homo sapiens
2 OBJECTIVE: Based on the antitumor function of the delta-tocotrienol, shed light on the relationship between the proliferation inhibition effect of delta-tocotrienol on human colon cancer cells SW620 with Wnt signal pathway. tocotrienol, delta Wnt family member 1 Homo sapiens
3 OBJECTIVE: Based on the antitumor function of the delta-tocotrienol, shed light on the relationship between the proliferation inhibition effect of delta-tocotrienol on human colon cancer cells SW620 with Wnt signal pathway. tocotrienol, delta Wnt family member 1 Homo sapiens
4 Detected the expressions level of the factors related to Wnt signal pathway via Western bloting and immunocytochemistry, to observe the influence of delta-tocotrienol on Wnt-1, beta-catenin, c-jun, cylin D1. tocotrienol, delta Wnt family member 1 Homo sapiens
5 CONCLUSION: The proliferation inhibition effect of delta-tocotrienol on colon cancer cell may correlate with the ability of delta-tocotrienol to downregulate the expression levels of wnt-1, beta-catenin, c-jun, cylin D1 in the Wnt signal pathway. tocotrienol, delta Wnt family member 1 Homo sapiens
6 CONCLUSION: The proliferation inhibition effect of delta-tocotrienol on colon cancer cell may correlate with the ability of delta-tocotrienol to downregulate the expression levels of wnt-1, beta-catenin, c-jun, cylin D1 in the Wnt signal pathway. tocotrienol, delta Wnt family member 1 Homo sapiens
7 CONCLUSION: The proliferation inhibition effect of delta-tocotrienol on colon cancer cell may correlate with the ability of delta-tocotrienol to downregulate the expression levels of wnt-1, beta-catenin, c-jun, cylin D1 in the Wnt signal pathway. tocotrienol, delta Wnt family member 1 Homo sapiens
8 CONCLUSION: The proliferation inhibition effect of delta-tocotrienol on colon cancer cell may correlate with the ability of delta-tocotrienol to downregulate the expression levels of wnt-1, beta-catenin, c-jun, cylin D1 in the Wnt signal pathway. tocotrienol, delta Wnt family member 1 Homo sapiens